Table 1.
Characteristic | No. (%) |
---|---|
Age, y, median (IQR) | 61 (53–70) |
Sex | |
Male | 47 (68) |
Female | 22 (32) |
Country | |
United States | 66 (96) |
Southeast | 26 (38) |
Midwest | 21 (30) |
Southwest | 14 (20) |
West | 4 (4) |
Northeast | 1 (1) |
International | 3 (4) |
Immunocompromising condition | |
None | 36 (52) |
Solid organ transplant | 15 (22) |
Malignancy on chemotherapy | 8 (12) |
Other chronic immunosuppression | 7 (10) |
HIV | 5 (7) |
Other | 2 (3) |
Comorbidity | |
Diabetes | 28 (41) |
Any chronic immunosuppressant | 27 (39) |
Multiple agents | 16 (23) |
Glucocorticoids | 17 (25) |
Calcineurin inhibitors | 13 (19) |
Antimetabolite | 11 (16) |
T-cell co-stimulation blocker | 2 (3) |
Alkylating agent | 2 (3) |
Tyrosine kinase inhibitor | 2 (3) |
Anti-CD20 | 1 (1) |
mTOR inhibitor | 1 (1) |
Year of COVID-19 diagnosis | |
2020 | 15 (22) |
2021 | 40 (58) |
2022 | 8 (12) |
Unknown | 5 (7) |
COVID-19 treatment | |
Hospitalization for COVID-19 | 56 (81) |
Supportive care only | 13 (19) |
Any immunosuppressant | 51 (74) |
Glucocorticosteroids | 50 (72) |
IL-6 inhibitor | 7 (10) |
JAK inhibitor | 5 (7) |
Antiviral | 39 (57) |
Remdesivir | 38 (55) |
Paxlovid | 1 (1) |
Antibody | 15 (22) |
Convalescent plasma | 9 (13) |
Monoclonal antibodies | 6 (9) |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: COVID-19, coronavirus disease 2019; HIV, human immunodeficiency virus; IL-6, interleukin 6; IQR, interquartile range; JAK, Janus kinase; mTOR, mammalian target of rapamycin.