Figure 2.

Effect of SophorOx^TM on serum 8-isoprostane levels. Group 1: animals were exercised and no treatment; group 2: animals received SophorOx™ (500 mg·kg⁻¹·b.w); group 3: animals were exercised and received SophorOx™ orally (500 mg·kg⁻¹·b.w). Group 4 (G4): standard control was not exercised and no SophorOx™ was administered. All results were expressed as mean ± SD (n = 6). Data analysis (GraphPad Prism Software Version 7.04, San Diego, CA, USA) was performed using one-way ANOVA followed by Dunnett's test for multiple comparisons. 8-Iso-PGF2α levels of the G3 groups showed significant changes from week 1 to the end of the treatment period. ^∗Statistically significant (p < 0.05) in comparison with G4.