Table 1.

Performance of DiAna translation.

Active substance	Formatting (n occurrences)	RxNorm (n occurrences)	DiAna (n occurrences)	DiAna/RxNorm	DiAna/formatting
Paracetamol	112,939	(–)	1,040,051	(–)	9.21
Acetylsalicylic acid	61,652	(–)	942,051	(–)	15.28
Adalimumab	21,403	699,331	727,730	1.04	34.00
Etanercept	19,332	632,130	638,427	1.01	33.02
Levothyroxine	55,115	288,916	604,688	2.09	10.97
Ranitidine	69,874	69,883	597,604	8.55	8.55
Methotrexate	224,467	230,866	553,011	2.40	2.46
Prednisone	177,872	181,092	552,531	3.05	3.11
Omeprazole	132,069	273,775	539,760	1.97	4.09
Insulin	73,619	(–)	539,088	(–)	7.32
Metformin	279,461	320,567	534,234	1.67	1.91
Atorvastatin	210,528	421,702	529,453	1.26	2.51
Calcium	150,507	(–)	513,772	(–)	3.41
Amlodipine	250,232	347,454	508,501	1.46	2.03
Furosemide	99,789	269,463	472,999	1.76	4.74
Oxycodone	98,512	287,818	462,109	1.61	4.69
Salbutamol	40,326	(–)	435,816	(–)	10.81
Pantoprazole	182,322	288,211	421,710	1.46	2.31
Metoprolol	76,981	104,124	420,331	4.04	5.46
Magnesium	68,548	(–)	414,166	(–)	6.04
Fluticasone	12,549	91,204	397,614	4.36	31.68
Lenalidomide	27,201	370,133	380,151	1.03	13.98
Hydrochlorothiazide	72,069	(–)	380,068	(–)	5.27
Gabapentin	77,949	170,801	372,316	2.18	4.78
Dexamethasone	91,353	131,730	365,042	2.77	4.00
Lisinopril	125,376	150,113	361,929	2.41	2.89
Vitamin B9	100	(–)	356,564	(–)	3,565.64
Simvastatin	101,474	163,417	341,174	2.09	3.36
Vitamin D3	142,967	(–)	327,770	(–)	2.29
Hydrocodone	55,669	56,140	325,467	5.80	5.85

Drugs most frequently reported in the FAERS, after DiAna translation, relative to simple formatting and the merging with RxNorm. The number of occurrences in the three translations is reported together with the ratio of occurrences between DiAna and the others. In some cases, differences in the nomenclature resulted in empty cells

FAERS US FDA adverse event reporting system