Table 2.

Select tagging AGXT2 SNPs and pairwise linkage disequilibrium of AGXT2 polymorphisms

(A) Main characteristics of the select tagging AGXT2 SNPs in control subjects
AGXT2 SNP (major/minor allele)	Localization	HWE p value	MAF	Genotyping rate (%)
rs37370 (T/C)	Exon 3 (S102N)	0.18	G (0.45)	99.8
rs37369 (T/C)	Exon 4 (V140I)	0.01	C (0.36)	100
rs180749 (A/G)	Exon 6 (T212I)	0.29	G (0.21)	100
rs16899974 (C/A)	Exon 14 (V498L)	0.13	A (0.47)	99.95

(B) Pairwise linkage disequilibrium of AGXT2 polymorphisms (r2 below and D′ above the diagonal)
	rs37370	rs180749	rs16899974
rs37370		0.79	0.29
rs180749	0.13		0.37
rs16899974	0.08	0.03

MAF minor allele frequency

Two-sided P values less than 0.05 were considered statistically significant.