Fig. 1.

The integration of multi-omics analyses in individuals from cohorts can help to drive the development of precision medicine in diabetes. Legend: each layer represents increasing complexity which have arisen from the genome, epigenome, transcriptome, proteome, metabolome and exposome. These information, representing deep phenotyping of individuals, may provide information that can help inform and guide disease classification and treatment selection, as well as predict future risk of complications. Precision Medicine in Diabetes reflects the overall efforts to utilize these as well as clinical information to guide treatment selection and clinical decisions