Table 2.
Demographic and clinical characteristics of 858 ADNI participants at baseline analyzed in this study.
Diagnosis | NC (N = 284, 33.1%) | MCI (N = 459, 53.4%) | AD (N = 115, 13.4%) |
---|---|---|---|
Age (years) | 73.71 (5.80) | 71.85 (7.40) | 74.92 (8.30) |
Women | 145 (51.0%) | 189 (41.1%) | 43 (37.3%) |
Education (years) | 16.52 (2.61) | 16.22 (2.76) | 15.70 (2.72) |
CDR-SOB | 0.05 (0.21) | 1.32 (1.00) | 3.90 (2.14) |
MMSE | 27.07 (7.35) | 24.88 (8.89) | 20.23 (8.11) |
CSF A | 199.42 (51.75) | 173.82 (52.59) | 137.27 (35.72) |
CSF P-tau | 32.8 (16.56) | 39.69 (20.86) | 53.03 (22.97) |
P-tau/A ratio | 0.19 (0.13) | 0.27 (0.19) | 0.41 (0.21) |
Data are number (%) or mean (s.d.).
AD Alzheimer’s disease, ADNI Alzheimer’s Disease Neuroimaging Initiative, CDR-SOB clinical dementia rating-sum of boxes, CSF cerebrospinal fluid, NC normal controls, MCI mild cognitive impairment, MMSE Mini-Mental Status Examination.