FIG. 4.
Effect of intragastric priming with CT on specific genital (A) and rectal (B) ASC responses after vaginal and rectal CT booster immunization, respectively. Monkeys received three intragastric doses of CT followed by one vaginal or rectal dose. ASC responses were measured 7 days after booster immunization. Data are expressed as geometric mean numbers (bars) and individual values (circles) for CT-specific IgA (closed symbols) and IgG (open symbols). The dashed lines denote the limit (30 ASC per 106 MNC) below which net values were considered negative (99% confidence interval).