Table 1.

Amounts of Vapor Exposure for Each Group

Vapor group	N (50% female)	Vehicle conditioning days			THC conditioning days
		VEH	Puffs (n×length)	Exposure duration (minutes)	THC concentration (mg/mL)	Puffs	Exposure duration (minutes)	Calculated THC dose (mg)
No THC	24	100% PG	5×6s	30	0 (100% PG)	5×6s	30	0
Low THC	24	100% PG	5×6s	30	100	5×6s	30	7
Medium THC	24	100% PG	5×6s	30	200	5×6s	30	10
High THC	24	100% PG	10×6s	30	200	10×6s	30	17

Each puff was delivered at equally set intervals (e.g., 2.5–5 min apart) across the 30-min session. Estimated total THC drug amounts (mg) delivered per exposure session were calculated based on volume delivered (determined by tank weights before and after sessions) and THC concentration in e-liquid; Note: air flow is continuous, and vaporized drug is pulled out into the exhaust system.

PG, propylene glycol; THC, Δ⁹-tetrahydrocannabinol; VEH, vehicle.