Figure 3.

Enhancers governing self-renewing identity in naive endoderm and pluripotency

(A) Euler diagram defining an intersect of pluripotency enhancers: enhancers active in both 2iLIF and NACL.

(B) Euler diagram comparing pluripotency enhancers (intersect from A) with PrE enhancers.

(C–E) Genome browser tracks of H3K27ac and H3K4me1 across conditions 2iLIF, NACL, and nEnd of loci Nanog (C), Gata4 (D), and Tfcp2l1 (E) with examples of pluripotency enhancers (blue), PrE enhancers (pink), and common enhancers (gray) defined in (B).

(F–H) GO terms of the biological processes of pluripotency enhancers (F), PrE enhancers, (G) and common enhancers (H).