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. 2024 Feb 18;14:4000. doi: 10.1038/s41598-024-54400-6

Table 1.

Mean Drug Sensitivity Scores, DSS3, of pre-B-ALL cell lines to a panel of autophagy and lysosomal inhibitors (n = 3).

DRUG/Compound COG-LL-355h REH MHH-CALL-2 RCH-ACV SEM KASUMI-9
Chloroquine 22.5 28.3 20.6 9.5 5.3 2.1
Hydroxychloroquine 19 13.4 11.1 10.1 1.7 4
LYS-05 29.5 21.1 15 15.4 6.4 5.3
PIK-III 29 27.6 21 22 20.7 7.6
SAR405 7 8.9 10.7 14.5 11 4.3
ULK-101 1.4 4.3 2.8 0 28.1 4.4
L309-1226 21.6 16.5 9.4 7.2 11.1 4.8

Higher DSS values indicate higher sensitivity.