Table 3.
Mean ΔZIP synergy scores for the drug combinations of ALL patient samples (n = 3).
Drug combination | Pre-B-ALL | T-ALL | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
A5085 | A2808 | A4068 | A4348 | A5272 | A4333 | A3834 | A4253 | A2315 | A2664 | A5126 | |
Lys05-Dexamethasone | 6.5 | 13.44 | 7.6 | 4.28 | 8.54 | 8.45 | 2.31 | 11.21 | 5.68 | 13.63 | 14.05 |
SAR405-Dexamethasone | N/A | N/A | 2.51 | 0.31 | 7.6 | N/A | N/A | N/A | 2.12 | − 1.22 | N/A |
PIKIII-Dexamethasone | N/A | 3.82 | 6.1 | 4.23 | 20.92 | N/A | 0.74 | 12.17 | 12.02 | 9.3 | 6.68 |
HCQ-Dexamethasone | N/A | N/A | 10.33 | 12.3 | 20.98 | N/A | N/A | 5.47 | 10.32 | 14.68 | N/A |