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. 2024 Feb 18;14:4025. doi: 10.1038/s41598-024-54068-y

Table 3.

Markers of nitric oxide metabolism.

Regular diet Western diet
Mouthwash
saline
Mouthwash
chlorhexidine
t-test
p-value
Mouthwash
saline
Mouthwash
chlorhexidine
t-test
p-value

Plasma

Nitrate

(µM)

31.05 ± 13.82 23.45 ± 9.61 0.2453 32.51 ± 6.51 32.88 ± 9.31 0.9044

Plasma

Nitrite

(µM)

1.51 ± 0.72 0.40 ± 0.20 0.0209 1.29 ± 0.50 1.46 ± 0.49 0.4508

Urinary

Nitrate

(µM)

368.5 ± 291.6 310.2 ± 229.1 0.6935 525.9 ± 124.9 488.5 ± 208.7 0.6160

Urinary

Nitrite

(µM)

1.60 ± 0.55 2.19 ± 0.89 0.1513 3.82 ± 1.97 2.84 ± 0.90 0.1349

RBC

Heme-NO

(a.u.)

10.56 ± 4.69 5.15 ± 3.10 0.0226 6.05 ± 1.90 4.77 ± 2.51 0.5688

Plasma and urinary concentrations of nitrate and nitrite, and heme-NO signal in blood, determined by electron paramagnetic resonance. n = 12 mice in each experimental group. Data expressed in Mean ± SD. Red blood cell (RBC), Arbitrary units (a.u.).