TABLE 1.

Kex2 and yapsin activities of wild-type and disruptant strains^a

Strain	Relative activity (%) of:
	Kex2	Yapsin
Wild type	100 ± 2	100 ± 1
kex2	1 ± 1	200 ± 4
yps1	96 ± 0.4	5 ± 3
kex2 yps1	1.0 ± 0.5	11 ± 3
Wild typeb	2.4 ± 0.4	6 ± 4

^aValues are means ± standard deviations (n = 3) and are expressed as percentages of the mean wild-type activities (1.7 and 0.037 nmol/min per mg of solubilized membrane protein for the Kex2 and yapsin assays, respectively).

^bControl reactions in which the Kex2 assay contained the chelator EGTA instead of the Ca²⁺ cofactor and in which the yapsin assay contained the aspartic protease inhibitor pepstatin. The accessory aminopeptidase M used in the yapsin assay was basically unaffected by pepstatin (not shown).