| Study | Reason for exclusion |
|---|---|
| Frohman 2004 | Retrospective review |
| Frohman 2010 | Six‐month follow‐up study without our specified 12‐month follow‐up outcome measures |
| NCT00618527 | Experimental study that was "completed" in May 2012 (as reported on clinicaltrials.gov). Outcome measures did not fulfil our inclusion criteria |
| Remington 2010 | Study authors enrolled both participants with early RRMS and those with clinically isolated syndrome (CIS). Details of RRMS and CIS were not available |
| Vermersch 2007 | Case series study of 30 participants with RRMS treated with MMF in combination with IFN without a control group |
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