Table 3.

Definitions for DORIS-remission and LLDAS

Features	DORIS-remission	LLDAS
Main purpose	Defines a state of remission in SLE	Represents a state of low disease activity in SLE
Disease Activity Score	Clinical SLEDAI=0	SLEDAI-2K ≤4 with no activity in major organ systems (renal, CNS, cardiopulmonary, vasculitis, fever), and no haemolytic anaemia or gastrointestinal activity
		No new lupus disease activity compared with the previous assessment
Physician Global Assessment	<0.5 (0–3)	≤1 (0–3)
Glucocorticoids	Prednisolone ≤5 mg/day or equivalent	Prednisolone ≤7.5 mg/day or equivalent
Other treatments	Stable antimalarials, immunosuppressives and biologics	Well-tolerated standard maintenance doses of immunosuppressive drugs and approved biological agents

CNS, central nervous system; DORIS, Definitions Of Remission In SLE; LLDAS, Lupus Low Disease Activity State; SLEDAI-2K, SLE Disease Activity Index 2000.