Table 4.

SLE-specific Quality of Life Questionnaire

Questionnaire	Lupus Quality of Life	SLE Quality of Life	Lupus Patient-Reported Outcome (LupusPRO)	Lupus Impact Tracker
Country of development	UK	Singapore	USA	USA
Number of items	34	40	43	10 from LupusPRO
Domains	Eight domains: physical health, emotional health, body image, pain, planning, fatigue, intimate relationships, burden to others	six domains: physical function, activities, symptoms, treatment, mood, self-image	Eight domains: symptoms, cognition, treatments, reproduction, physical health, pain/vitality, emotional health, body image, goals/aspirations, social support, coping, satisfaction with care	A unique dimension representing the impact of lupus
Time to complete	<10 min	<10 min	7–10 min	<5 min
Questions	5-point Likert scale (0–4)	7-point Likert scale1–8	5-point Likert scale (0–4)	5-point Likert scale (0–4)
Recall period	4 weeks	1 week	4 weeks	4 weeks
Scoring	Sum of items score by domain divided by 4 and multiplied by 10	A summary score: sum of all items. Domain scores: sum of item responses by domain	Sum of items score by domain divided by 4 and multiplied by 10	Sum of items score by domain divided by 4 and multiplied by 10
Interpretation	0: worst possible QoL to 100: best possible QoL	Overall score from 40 to 280 (the higher the score, the lower the QoL), score range varies by domain	0: worst possible QoL to 100: best possible QoL	0: no impact of lupus to 100: highest possible impact of lupus
Minimal clinically important difference	3–7 (depends on domain)	An average increase of 25 points has been described in patients reporting an improvement in their clinical condition	An increase in score of between 3 and 8 points, depending on the domain, was noted in patients presenting an improvement in their activity criteria	A mean improvement of 8 points was described in SRI-4 responders. A mean improvement of −4.2 points was noted in patients reporting an improvement in their clinical condition

QoL, quality of life.