Table 1.

Demographic and clinical characteristics of the STAAMP cohort with TEG samples stratified by TXA

Variable	Overall (n=837)	Placebo (n=430)	TXA (n=407)	P value
Age	38.0 (26.0–55.0)	39.0 (26.0–56.0)	38.0 (26.0–51.0)	0.20
Male	624 (74.6%)	322 (74.9%)	302 (74.2%)	0.82
Blunt Injury	702 (83.9%)	366 (85.1%)	336 (82.6%)	0.31
TBI	196 (23.4%)	100 (23.3%)	96 (23.6%)	0.92
ISS	12.0 (5.0–22.0)	11.0 (4.0–22.0)	12.0 (5.0–22.0)	0.39
Prehospital GCS	15.0 (12.0–15.0)	14.0 (11.0–15.0)	15.0 (12.0–15.0)	0.25
Transfer	113 (13.7%)	57 (13.4%)	56 (14.0%)	0.78
Prehospital Intubation	204 (24.4%)	109 (25.3%)	95 (23.3%)	0.50
Prehospital SBP	125.0 (88.0–147.0)	126.0 (88.0–148.0)	124.0 (88.0–144.0)	0.89
24-hour whole blood	0.0 (0.0–1.0)	0.0 (0.0–1.0)	0.0 (0.0–1.0)	0.64
24-hour PRBC	0.0 (0.0–1.0)	0.0 (0.0–1.0)	0.0 (0.0–1.0)	0.50
24-hour plasma	0.0 (0.0–0.0)	0.0 (0.0–0.0)	0.0 (0.0–0.0)	0.11
24-hour platelets	0.0 (0.0–0.0)	0.0 (0.0–0.0)	0.0 (0.0–0.0)	0.85
INR	1.1 (1.0–1.2)	1.1 (1.0–1.2)	1.1 (1.0–1.2)	0.77
Lactate	2.7 (1.8–3.9)	2.6 (1.8–4.1)	2.8 (1.8–3.8)	0.97
30-day mortality	57 (6.8%)	35 (8.1%)	22 (5.4%)	0.12
MOF	69 (8.2%)	37 (8.6%)	32 (7.9%)	0.70
VTE	35 (4.2%)	13 (3.0%)	22 (5.4%)	0.09

Values are represented by numbers (percentages) and means (IQR). TXA refers to patients who received prehospital tranexamic acid (TXA).

GCS, Glasgow Coma Scale; INR, international normalized ratio; ISS, Injury Severity Score; MOF, multiple organ failure; PRBC, packed red blood cells; SBP, systolic blood pressure; STAAMP, Study of Tranexamic Acid During Air Medical and Ground Prehospital Transport; TBI, traumatic brain injury; TEG, thromboelastography; transfer, transferred from another hospital; VTE, venous thromboembolism.