TABLE 1:
Demographics of the BUP, Methadone, and OUD Cohorts
| B-MOUD Patient Cohort (n=40,431) | M-MOUD Patient Cohort (OUD without receipt of B-OUD) (n=10,281) | OUD Patient Cohort (OUD without receipt of B-OUD or M-OUD) (n=205,014) | |||||
|---|---|---|---|---|---|---|---|
| n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | ||
| Age | Mean, std and (95% CI) | 43.6 (13.5) | 43.5–43.8 | 52.5 (9.9) | 52.3–52.7 | 52.8 (13.1) | 52.8–52.9 |
| 18–29 | 9031 | 22.3 (21.922.7) | 514 | 5.0 (4.6–5.4) | 14859 | 7.3 (7.1–7.4) | |
| 30–39 | 8828 | 21.8 (21.422.2) | 650 | 6.3 (5.9–6.8) | 22981 | 11.2 (11.1–11.3) | |
| 40–49 | 7162 | 17.7 (17.318.1) | 1806 | 17.6 (16.8–18.3) | 33315 | 16.3 (16.1–16.4) | |
| 50–59 | 10470 | 25.9 (25.526.3) | 5522 | 53.7 (52.7–54.7) | 71325 | 34.8 (34.6–35.0) | |
| 60+ | 4939 | 12.2 (11.912.5) | 1789 | 17.4 (16.7–18.1) | 62529 | 30.5 (30.3–30.7) | |
| Unknown | 1 | 0 (0.0–0.0) | 0 | 0 (0.0–0.0) | 5 | 0 (0.0–0.0) | |
| Gender | Male | 37503 | 92.8 (92.5–93.0) | 9953 | 96.8 (96.4–97.1) | 191586 | 93.5 (93.3–3.6) |
| Race | White | 32293 | 79.9 (79.5–80.3) | 4868 | 47.4 (46.4–48.3) | 140629 | 68.6 (68.4–68.8) |
| Black | 5523 | 13.7 (13.3–14.0) | 4618 | 44.9 (44.0–45.9) | 47118 | 23.0 (22.8–23.2) | |
| Other | 2615 | 6.5 (6.2–6.7) | 795 | 7.7 (7.2–8.3) | 17267 | 8.4 (8.3–8.5) | |
| Ethnicity | Not Hispanic/ Latino | 37047 | 91.6 (91.491.9) | 9261 | 90.1 (89.5 90.6) | 186344 | 90.9 (90.891.0) |
| Hispanic/Latino | 2281 | 5.6 (5.4–5.9) | 740 | 7.2 (6.7–7.7) | 10982 | 5.4 (5.3–5.5) | |
| Unknown | 1103 | 2.7 (2.6–2.9) | 280 | 2.7 (2.4–3.1) | 7688 | 3.8 (3.7–3.8) | |
| MENTAL HEALTH CONDITIONS | |||||||
| Any Mental Health Condition | 29241 | 72.3 (71.972.8) | 5808 | 56.5 (55.5–57.4) | 157133 | 76.7 (76.5–76.8) | |
| Depressive disorders | 18772 | 46.4 (45.946.9) | 3514 | 34.2 (33.3–35.1) | 107122 | 52.3 (52.0–52.5) | |
| Trauma- and stressor-related disorders | 15035 | 37.2 (36.737.7) | 2601 | 25.3 (24.5–26.1) | 79546 | 38.8 (38.6–39.0) | |
| Anxiety and fear-related disorders | 11775 | 29.1 (28.729.6) | 1536 | 14.9 (14.3–15.6) | 58529 | 28.6 (28.4–28.7) | |
| Suicidal ideation/attempt/intentional self-harm | 4411 | 10.9 (10.611.2) | 519 | 5.1 (4.6–5.5) | 30077 | 14.7 (14.5–14.8) | |
| Bipolar and related disorders | 3775 | 9.3 (9.1–9.6) | 597 | 5.8 (5.4–6.3) | 24171 | 11.8 (11.7–11.9) | |
| Other specified and unspecified mood disorders | 2943 | 7.3 (7.0–7.5) | 373 | 3.6 (3.3–4.0) | 19826 | 9.7 (9.5–9.8) | |
| Personality disorders | 2521 | 6.2 (6.0–6.5) | 549 | 5.3 (4.9–5.8) | 18616 | 9.1 (9.0–9.2) | |
| Schizophrenia spectrum and other psychotic disorders | 2488 | 6.2 (5.9–6.4) | 856 | 8.3 (7.8–8.9) | 25196 | 12.3 (12.1–12.4) | |
| Disruptive, impulse-control and conduct disorders | 990 | 2.5 (2.3–2.6) | 245 | 2.4 (2.1–2.7) | 7471 | 3.6 (3.6–3.7) | |
| Somatic symptom disorders | 862 | 2.1 (2.0–2.3) | 186 | 1.8 (1.6–2.1) | 5533 | 2.7 (2.6–2.8) | |
| Obsessive-compulsive and related disorders | 386 | 1.0 (0.9–1.1) | 55 | 0.5 (0.1–1.1) | 2326 | 1.1 (1.1–1.2) | |
| Miscellaneous mental and behavioral disorders/conditions | 3194 | 7.9 (7.6–8.2) | 878 | 8.5 (8.0–9.1) | 23308 | 11.4 (11.2–11.5) | |
| SUBSTANCE USE CONDITIONS | |||||||
| Tobacco-related disorders | 14933 | 36.9 (36.537.4) | 3943 | 38.4 (37.4–39.3) | 84363 | 41.2 (40.9–41.4) | |
| Alcohol-related disorders | 11670 | 28.9 (28.429.3) | 3010 | 29.3 (28.4–30.2) | 83854 | 40.9 (40.7–41.1) | |
| Stimulant-related disorders | 7737 | 19.1 (18.819.5) | 2964 | 28.8 (28.0–29.7) | 52362 | 25.5 (25.4–25.7) | |
| Inhalant-related disorders | 7183 | 17.8 (17.418.1) | 1738 | 16.9 (16.2–17.6) | 31662 | 15.4 (15.3–15.6) | |
| Amphetamine-related disorders | 3578 | 8.9 (8.6–9.1) | 532 | 5.2 (4.8–5.6) | 11271 | 5.5 (5.4–5.6) | |
| Cannabis-related disorders | 5443 | 13.5 (13.113.8) | 994 | 9.7 (9.1–10.3) | 40750 | 19.9 (19.7–20.1) | |
| Sedative-related disorders | 2830 | 7.0 (6.8–7.3) | 628 | 6.1 (5.7–6.6) | 14388 | 7.0 (6.9–7.1) | |
| Hallucinogen-related disorders | 430 | 1.1 (1.0–1.2) | 85 | 0.8 (0.6–1.0) | 2720 | 1.3 (1.3–1.4) | |
| Other specified substance-related disorders | 14924 | 36.9 (36.437.4) | 4063 | 39.5 (38.6–40.5) | 67138 | 32.8 (32.5–33.0) | |
| Mental and substance use disorders in remission | 7726 | 19.1 (18.719.5) | 2490 | 24.2 (23.4–25.1) | 59375 | 29.0 (28.8–29.2) | |