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. Author manuscript; available in PMC: 2024 Feb 19.
Published in final edited form as: J Autoimmun. 2019 Nov 12;107:102355. doi: 10.1016/j.jaut.2019.102355

Table 2.

Fractions of activated platelets with characteristic structural features under various experimental conditions (from transmission electron microscopy)

Structural platelet variants Platelets treated with: Untreated platelets
anti-DNA Abs anti-DNA Abs + DNA anti-Fc mAb + anti-DNA Abs anti-Fc mAb + anti-DNA Abs + DNA non-DNA binding IgG
Total platelets taken as 100%
(n*)
100
(n=131)
100
(n=164)
100
(n=38)
100
(n=107)
100
(n=27)
100
(n=262)
Activated platelets, % 87 98 78 73 26 16
centered α-granules, % 7 4 14 7 0 0
merged α- granules, % 6 15 0 2 0 0
no α-granules, % 8 9 0 0 0 0
Cytoplasmic fragmentation, % 11 13 0 0 0 0
Platelet “ghosts”, % 0 10 0 0 0 0
*

n is the absolute number of individual platelets analyzed