Extended Data Table 1 |.

Baseline and post-treatment cognitive and functional status assessments

Cognitive Test	Baseline Mean (SD)	Post-Treatment Mean (SD)	T-test(df), p-value, 95% CI
MoCA	16.2 (2.9)	16.0 (2.5)	t(4)=−0.196, p=0.85, −3.031 – 2.63
CDR Sum of Boxes	5.30 (2.2)	5.60 (2.0)	t(4)=2.449, p=0.070, −0.04 – 0.64
HVLT-R Immediate Total Recall	13.80 (4.4)	10.20 (4.6)	t(4)=−3.674, p=0.021*, −6.32 – −0.88
HVLT-R Delayed Recall	0.60 (0.9)	0.40 (0.9)	t(4)=−1.000, p=0.37, 0.76 – 0.36
WMS Logical Memory Immediate Recall	12.6 (6.5)	13.2 (1.9)	t(4)=0.220, p=0.84, −6.98 – 8.18
WMS Logical Memory Delayed Recall	14.2 (2.2)	12.0 (2.8)	t(4)=−1.633, p=0.18, −2.16 – 0.56
Benson Figure Copy	8.60 (6.2)	14.6 (2.5)	t(4)=2.390, p=0.075, −0.97 – 12.97
Benson Figure Delayed Recall	0.80 (1.5)	2.50 (3.1)	t(4)=2.049, p=0.13, −0.97 – 4.47
Number Span Forward	6.40 (1.8)	6.80 (1.6)	t(4)=0.784, p=0.48, −1.02 – 1.82
Number Span Backward	4.60 (1.7)	4.80 (1.3)	t(4)=0.343, p=0.75; −1.42 – 1.82

Baseline to post-treatment changes were assessed using paired samples t-tests, 95% CI: 95 percent confidence interval for the post vs. baseline mean difference, p < 0.05. MoCA = Montreal Cognitive Assessment, CDR = Clinical Dementia Rating scale, HVLT-R = Hopkins Verbal Learning Test Revised, WMS = Wechsler Memory Scales, Trails = Trail Making Test, IADL = Independent Activities of Daily Living, ADL = Activities of Daily Living, GDS-15 = Geriatric Depression Scale 15-Item, NPI = Neuropsychiatric Inventory.