Table 3.
Incidence of bloodstream infections among neonates with central venous catheters by line-days in three tertiary care neonatal intensive care units in Pune, India, May 1, 2017 - July 31, 2019
| Line day | BSI | Line-days | Incidence per 1000 line-days |
IRR | 95% CI |
|---|---|---|---|---|---|
| 3–4 | 40 | 2449 | 16.3 | REF | |
| 5–6 | 33 | 1884 | 17.5 | 1.07 | (0.66–1.74) |
| 7–8 | 19 | 1247 | 15.2 | 0.93 | (0.51–1.65) |
| 9–10 | 13 | 793 | 16.4 | 1.00 | (0.49–1.92) |
| 11–12 | 10 | 522 | 19.2 | 1.17 | (0.52–2.39) |
| 13–14 | 4 | 350 | 11.4 | 0.70 | (0.18–1.94) |
| 15–16 | 2 | 246 | 8.1 | 0.50 | (0.06–1.92) |
| 17–18 | 4 | 176 | 22.7 | 1.39 | (0.36–3.85) |
| 19–20 | 1 | 130 | 7.7 | 0.47 | (0.01–2.78) |
| 21–22 | 0 | 94 | 0 | — | |
| 23–24 | 0 | 74 | 0 | — | |
| 25–26 | 1 | 56 | 17.9 | 1.09 | (0.27–6.45) |
| 27–28 | 0 | 37 | 0 | — | |
| 29–30 | 1 | 32 | 31.3 | 1.91 | (0.05–11.29) |
Comparison of BSI incidence by two-day interval in neonates with a CVC in place. Day of insertion is day 1; risk for BSI with CVC begins at line day 3. Analysis is censored at day 30; very few lines remained in place for >30 days and no BSI events occurred. Abbreviations: BSI – bloodstream infection; CI – confidence interval; IRR – incidence rate ratio.