Table 1.
Characteristics of Study Participants
| BLSA | InCHIANTI | ||||
|---|---|---|---|---|---|
| Trait (unit) | n | Mean ± SD or % | n | Mean ± SD or % | p Value |
| Age (y) | 240 | 57.5 ± 19.8 | 963 | 66.2 ± 15.2 | <.001 |
| Sex (% women) | 240 | 50% | 963 | 56% | <.001 |
| Waist circumference (cm) | 240 | 87.1 ± 12.0 | 947 | 91.2 ± 10.8 | <.001 |
| BP, systolic (mmHg) | 240 | 113.5 ± 13.8 | 963 | 144.2 ± 21.5 | <.001 |
| BP, diastolic (mmHg) | 240 | 68.1 ± 8.8 | 963 | 82.5 ± 9.4 | <.001 |
| Glucose (mg/dL) | 236 | 87.4 ± 8.7 | 961 | 93.6 ± 23.8 | <.001 |
| IL6 (pg/ml) | 240 | 3.7 ± 2.8 | 961 | 1.8 ± 3.2 | <.001 |
| CRP (μg/ml) | 238 | 2.1 ± 2.8 | 949 | 4.0 ± 6.6 | <.001 |
| RDW (%) | 239 | 13.3 ± 0.8 | 955 | 13.5 ± 0.9 | <.001 |
| BUN (mg/dl) | 240 | 15.7 ± 4.5 | 961 | 33.1 ± 8.8 | <.001 |
| Alkaline phosphatase (units/L) | 240 | 70.4 ± 17.9 | 961 | 200.2 ± 98.2 | <.001 |
| Albumin (g/dl) | 240 | 3.9 ± 0.3 | 961 | 4.3 ± 0.3 | <.001 |
| Gait speed (m/s) | 234 | 1.3 ± 0.2 | 941 | 1.1 ± 0.3 | <.001 |
| Grip strength (kg) | 240 | 35.3 ± 12.0 | 836 | 31.9 ± 13.9 | <.001 |
Notes: BLSA = Baltimore Longitudinal Study of Aging; BUN = blood urea nitrogen; CRP = C-reactive protein; IL6 = Interleukin-6; RDW = red cell distribution width.
p Value based on comparison of values between BLSA and InCHIANTI using 2-sample, 2-sided t test for continuous traits and χ2 test for categorical traits. t Test was performed using log-transformed glucose, IL6, and CRP values.