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Lowest-energy conformations of 2′-O-Me-C and 2′-C-Me-C. Conformations were determined by molecular mechanics calculations and are presented as schematic diagrams with the calculated energy differences obtained between the predicted lowest-energy conformers of the Northern furanose and Southern furanose puckers in panel A. Stereo views are shown as tubes in panel B, colored by element (grey = C, blue = N, red = 0, white = 0).
