FIGURE 2.

The formation and biological characteristics of EVs. (A) The formation of EVs; (B) Low immunogenicity. (C) Only a small number of EVs will accumulate in places such as the liver and kidneys, so there is little toxicity in the body; (D) EVs can pass through many kinds of biological barriers, such as the plasma membrane, the BBB and the cell barrier. APC, antigen‐presenting cell; BBB, the blood‐brain barrier; EV, extracellular vesicle; lncRNA, long non‐coding RNA; MHC, major histocompatibility complex; MVB, multivesicularbody