FIGURE 6.

Engineered EVs from different cell sources can be used to treat different diseases. (A) Mesenchymal stem cells, dendritic cells, and macrophages are a few examples of cells that may be employed to make EVs. (B) Each kind of cell has unique qualities that make it appropriate for the treatment of various disorders. EVs from various sources may be created to load therapeutic modalities, including medications, nucleic acids, and proteins, successfully into modified EVs. (C) The recipient cells may be chosen and given the modified EVs. The payload within the modified EVs is finally released for the precise therapy of numerous illnesses, including cancer, neurological disorders, and cardiovascular diseases, once it has been ingested and internalized by the recipient cells. DCs, dendritic cells; MΦ, macrophage cells; MSCs mesenchymal stem cells; MSCs‐EVs, external vesicles derived from mesenchymal stem cells miRNA, microRNA; siRNA, small/short interfering RNA