Table 1.
Characteristics of older adults with subclinical hypothyroidism
| Characteristic | Pretrial population (N = 2335) |
|---|---|
| Age, y | 72.9 (68.0-79.3) |
| Age ≥80 y, n (%) | 535 (22.9) |
| Female, n (%) | 1418 (60.7) |
| TSH, mIU/L | |
| First measurement (screening) | 5.40 (4.91-6.31) |
| >7 mIU/L, n (%) | 368 (15.8) |
| >10 mIU/L, n (%) | 57 (2.4) |
| Second measurement (trial baseline) | 4.02 (3.01-5.42) |
| fT4, pmol/L | |
| First measurement (screening)a | 13.6 (12.3-15.0) |
| Second measurement (trial baseline) | 13.0 (12.0-14.6) |
| Interval between first and second measurements | 344 (207-594) |
| <6 mo, n (%) | 465 (19.9) |
| 6-12 mo, n (%) | 778 (33.3) |
| >12 mo, n (%) | 1092 (46.8) |
| Season of second measurement (trial baseline), n (%) | |
| Summer | 764 (32.7) |
| Autumn | 735 (31.5) |
| Winter | 318 (13.6) |
| Spring | 518 (22.2) |
| Country, n (%) | |
| United Kingdom | 494 (21.2) |
| Ireland | 667 (28.6) |
| The Netherlands | 1174 (50.3) |
Values shown are median (interquartile range) unless indicated otherwise.
Abbreviation: fT4, free T4.
a First fT4 measurement was missing for n = 10.