Table 3.
Characteristics of older adults with persistent subclinical hypothyroidism
| Characteristic | In-trial placebo group (N = 361) |
|---|---|
| Age, y | 75.1 (69.6-81.4) |
| Age ≥ 80 y, n (%) | 113 (31.3) |
| Female, n (%) | 187 (51.8) |
| TSH, mIU/L | |
| First measurement (screening) | 5.84 (5.20-7.17) |
| Second measurement (trial baseline) | 5.75 (5.10-6.86) |
| >7 mIU/L, n (%) | 77 (21.3) |
| >10 mIU/L, n (%) | 16 (4.4) |
| Third measurement (follow-up) | 4.91 (3.96-6.49) |
| fT4 at second measurement (trial baseline), pmol/L | 13.4 (12.1-14.7) |
| Anti-TPO positive, n (%)a | 73 (25.3) |
| Interval between second and third measurements | 362 (345-370) |
| Country, n (%) | |
| United Kingdom | 64 (17.8) |
| Ireland | 50 (13.9) |
| The Netherlands | 149 (41.3) |
| Switzerland | 98 (27.1) |
Values shown are median (interquartile range) unless indicated otherwise.
Abbreviations: fT4, free T4; anti-TPO, thyroid peroxidase antibodies.
a Information on TPO antibodies was missing for n = 72.