Table 3.

Cluster information for all significant findings

Region	No. of voxels	Coordinates cluster peak
Main comparison between patients with Addison disease and controls Patients > Controls
Bilateral orbitofrontal cortex	775	X = −22, Y = 26, Z = −20
Left precuneus/lingual gyrus	88	X = 6, Y = −70, Z = 4
Left intracalcarine cortex/lingual gyrus	51	X = −14, Y = −90, Z = 0
Interaction between diagnostic group and mental fatigue
Left inferior lateral OCC Right lingual gyrus	74 68	X = −42, Y = −82, Z = −12 X = 14, Y = −82, Z = −8
Left intracalcarine cortex	66	X = −14, Y = −78, Z = 12
Interaction between diagnostic group and general fatigue
Left intracalcarine cortex	79	X = −2, Y = −82, Z = 16
Left inferior lateral OCC	58	X = −42, Y = −78, Z = 12
GC dose associated with rs-fc within patient group Positive associations:
Left orbitofrontal cortex	42	X = −30, Y = 38, Z = −4

Abbreviations: GC, glucocorticoid; OCC, occipital cortex; rs-fc, resting-state functional connectivity.