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Survival (A) and brain fungal burden (B) of BALB/c mice infected with C. bantiana intracranially and treated with posaconazole (POS) at a dose of 5, 15, 25, or 50 mg/kg/day for 28 days starting at day 1 postinfection. Mice were sacrificed for determination of tissue burden at days 1, 14, and 28 postchallenge. All control mice succumbed by day 14.
