FIG. 1.

LL-37, Bac2A, and indolicidin are not cytotoxic to THP-1 cells (A) or HBE cells (B) at concentrations ≤100 μg/ml. At 300 μg/ml, significant cytotoxicity was observed in indolicidin-treated HBE cells and in indolicidin- and LL-37-treated THP-1 cells. Mean values ± standard errors of the mean of three independent experiments are represented. A Student's t test was performed, and asterisks denote significance at a P value of <0.005 compared to cells treated with a vehicle control only.