FIG. 5.

Indolicidin induces IL-8 production in a dose-dependent manner in the human bronchial epithelial cell line 16HBE4o⁻. Cells were grown to confluency and subsequently incubated with indolicidin for 8 hours. The presence of IL-8 in the supernatant was detected by ELISA. Mean values ± standard errors of the means of one representative experiment of at least three are represented (n = 4 replicates for each condition). A two-tailed t test was performed, and results significant at a P value of <0.05 are marked with an asterisk.