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. 2005 May;49(5):1727–1732. doi: 10.1128/AAC.49.5.1727-1732.2005

TABLE 1.

Comparison of the activities of indolicidin, Bac2A, and LL-37

Property Minimal concn (μg/ml) demonstrating the given property
Reference(s) or source
Indolicidin Bac2A LL-37
MIC
    Gram positive (e.g., Staphylococcus aureus) 8 4 64 34, 37
    Gram negative (e.g., Pseudomonas aeruginosa) 64 8 64 37, 39
Antiendotoxin activity 5 20 1 Fig. 2
IL-8 production 10 ND (>100)a 10 2, 16, Fig. 5
Chemotaxis ND (>100)b 10 ND (>300)c Fig. 4
a

ND, not detectable at concentrations ≤100 μg/ml.

b

ND, chemotaxis was observed at 300 μg/ml (data not shown).

c

ND, not detectable at concentrations ≤300 μg/ml.