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A model of LLPS of the CPC leads to formation of bundle of MT. The CPC in liquid–liquid demixed state (I) sequesters free tubulin (II) increasing the tubulin concentration. That allows for nucleation and MT polymerization in such a way that MTs are parallel with minus end pointing outward (III). Such process leads to formation of MT bundles (IV). CPC, chromosomal passenger complex; LLPS, liquid–liquid phase separation; MT, microtubule.
