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. 2024 Feb 8;9(2):196–208. doi: 10.1016/j.synbio.2024.01.012

Table 1.

Plackett-Burman design matrix to screen beneficial parameters for S. baarnensis MH-133 antibacterial metabolite synthesis.

Run no. pH Incubation time (day) Cultivation method (rpm) Inoculum size (V/V) Temperature (°C) Magnesium chloride (g/l) Casein (g/l) Yeast extract (g/l) Starch (g/l) Elicitation (V/V) NaCl (g/l) inhibition zone diameter (mm)
1 9 12 0 4 25 13.2 0.5 3 15 6 15 16.5
2 7 12 200 8 25 4.4 0.5 3 5 10 15 9.5
3 7 12 200 4 35 13.2 1.5 1 5 6 15 13
4 9 4 200 8 25 13.2 1.5 3 5 6 5 16.5
5 9 12 200 4 25 4.4 1.5 1 15 10 5 0
6 7 4 0 8 25 13.2 1.5 1 15 10 15 0
7 7 4 200 4 35 13.2 0.5 3 15 10 5 0
8 7 4 0 4 25 4.4 0.5 1 5 6 5 9.5
9 9 4 200 8 35 4.4 0.5 1 15 6 15 13.5
10 9 12 0 8 35 13.2 0.5 1 5 10 5 0
11 9 4 0 4 35 4.4 1.5 3 5 10 15 0
12 7 12 0 8 35 4.4 1.5 3 15 6 5 21