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. 2024 Feb 8;9(2):196–208. doi: 10.1016/j.synbio.2024.01.012

Table 4.

Analysis of variance and coded coefficients for the experimental results of the Box-Behnken design.

Source DF Adj SS Adj MS F-Value P-Value
Model 5 319 63.8 49.9 0
Linear 4 283 70.75 55.33 0
Incubation time (day) 1 140.083 140.083 109.55 0
Inoculum size % (v/v) 1 30.083 30.083 23.53 0
Elicitation % (v/v) 1 60.75 60.75 47.51 0
yeast extract (g/l) 1 52.083 52.083 40.73 0
2-Way Interaction 1 36 36 28.15 0
Elicitation % (v/v)*yeast extract (g/l) 1 36 36 28.15 0
Error 21 26.852 1.279
Lack-of-Fit 19 26.185 1.378 4.13 0.212
Pure Error 2 0.667 0.333
Total 26 345.852
Coded Coefficients
Term Coef SE Coef T-Value P-Value VIF
Constant 15.074 0.218 69.27 0
Incubation time (day) 3.417 0.326 10.47 0 1
Inoculum size % (v/v) 1.583 0.326 4.85 0 1
Elicitation % (v/v) −2.25 0.326 −6.89 0 1
yeast extract (g/l) 2.083 0.326 6.38 0 1
Elicitation % (v/v)*yeast extract (g/l) −3 0.565 −5.31 0 1