Table 2.
Promising glycoproteins currently under investigation
| Glycoprotein | Encoding gene | Exam. methods | Refs. |
|---|---|---|---|
| HOMER3 | HOMER SCAFFOLD PROTEIN 3; HOMER3-19p13.11 | MS | Peixoto et al. (2021) |
| Fibronectin, laminin-5, and type IV collagen |
FIBRONECTIN 1; FN1-2q35 LAMININ, ALPHA-5; LAMA5-20q13.33 COL4A1-6; chromosomes 1, 2 and X |
SPRi | Guszcz et al. (2023) |
| GANAB protein |
GLUCOSIDASE, ALPHA, NEUTRAL AB; GANAB-11q12.3 |
IHC | Lin et al. (2022) |
| P4HB | PROCOLLAGEN-PROLINE, 2-OXOGLUTARATE-4-DIOXYGENASE, BETA SUBUNIT; P4HB-17q25.3 | Gene expression | Wu et al. (2021) |
| Leukocyte differentiation antigen CD36 |
CD36 ANTIGEN; CD36-7q21.11 |
TMA, IHC | Jeong et al. (2021) |
| CD93 (C1QR1) |
COMPLEMENT COMPONENT 1, q SUBCOMPONENT, RECEPTOR 1; C1QR1-20p11.21 |
Gene expression | Zheng et al. (2022) |
| Cartilage oligomeric matrix protein (COMP) | CARTILAGE OLIGOMERIC MATRIX PROTEIN; COMP-19p13.11 | IHC, RT-qPCR | Kuo et al. (2022) |
| Neurexophilin 4 |
NEUREXOPHILIN 4; NXPH4-12q13.3 |
Gene expression, IHC | Sun et al. (2022) |
| Alpha-2-Heremans-Schmid Glycoprotein (AHSG) |
ALPHA-2-HS-GLYCOPROTEIN; AHSG-3q27.3 |
Cell proliferation assay, WB, ELISA, IHC | Dong et al. (2022) |
| Fibulin-3 |
EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1; EFEMP1-2p16.1 |
IHC | Al Khader et al. (2022) |
| MUC1 |
MUCIN 1, CELL SURFACE ASSOCIATED; MUC1-1q22 |
Gene expression | Qing et al. (2022) |
| Human leukocyte antigen, DR alpha chain (HLA-DRA) |
MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS II, DR ALPHA; HLA-DRA-6p21.32 |
Gene expression | Piao et al. (2021) |
| Tenascin-C |
TENASCIN C; TNC-9q33.1 |
IHC, RT-qPCR, WB, … | Guan et al. (2022) |
| Vascular cell adhesion molecule-1 (VCAM-1) |
VASCULAR CELL ADHESION MOLECULE 1; VCAM1-1p21.2 |
Quantitative immunoassay | Mori et al. (2022) |
| Thrombospondin-5 (TSP-5) | CARTILAGE OLIGOMERIC MATRIX PROTEIN; COMP-19p13.11 | IHC | Harada et al. (2021) |
| Ribophorin II (RPN2) |
RIBOPHORIN II; RPN2-20q11.23 |
Gene expression, WB, IHC | Han et al. (2021) |
MS mass spectrometry; SPRi surface plasmon resonance imaging; IHC immunohistochemistry; TMA tissue microarray; RT-qPCR quantitative reverse transcription polymerase chain reaction; WB western blot; ELISA enzyme‐linked immunosorbent assay