TABLE 1.
Distribution of T and emm types and macrolide resistance phenotypes among 325 pharyngitis-associated erythromycin-resistant GAS in Portugal during 1998 to 2003
| T(emm)a | Resultb for yr:
|
Totalc | |||||
|---|---|---|---|---|---|---|---|
| 1998 | 1999 | 2000 | 2001 | 2002 | 2003 | ||
| 12(12) | 1/1 | 0/5 | 0/4 | 1/5 | 0/7 | 0/2 | 2 (1)/24 |
| 12(22) | 42/0 | 31/0 | 20/1 | 15/0 | 9/0 | 8/0 | 125 (113)/1 |
| 28(28) | 2/0 | 8/0 | 7/0 | 10/0 | 1/1 | 28 (2)/1 | |
| 1(1) | 0/3 | 0/11 | 0/17 | 0/4 | 0/35 | ||
| 25(75) | 0/3 | 0/5 | 0/3 | 0/11 | |||
| 4(4) | 0/5 | 0/1 | 0/6 | 0/2 | 0/6 | 0/12 | 0/32 |
| 12(11) | 2/0 | 2 (2)/0 | |||||
| B3264(4) | 0/2 | 0/2 | |||||
| 5/27/44(4) | 0/2 | 0/2 | |||||
| 1(12) | 0/2 | 0/2 | |||||
| NT(12)d | 0/2 | 0/4 | 0/1 | 0/7 | |||
| NT(28)d | 2/0 | 2/0 | |||||
| 13(22) | 3/0 | 3/0 | |||||
| 2(2) | 0/2 | 0/2 | |||||
| 2(4) | 0/2 | 0/2 | |||||
| 9(9) | 0/6 | 0/1 | 0/7 | ||||
| Othere | 2/0 | 1/2 | 1/4 | 5/4 | 2/5 | 1/8 | 12 (10)/23 |
| Total | 45/8 | 37/10 | 29/30 | 30/25 | 23/41 | 10/37 | 174/151 |
All T/emm type combinations presenting ≥2 isolates in any year of the study period are discriminated.
Number of isolates presenting each of the erythromycin resistance phenotypes (MLSB/M).
Numbers in parenthesis indicate tetracycline-resistant isolates among those presenting the MLSB phenotype. None of the isolates presenting the M phenotype was resistant to tetracycline.
NT, nontypeable by T serotyping.
Single isolates presenting unique T/emm-type combinations in each year. Most (16/24) of these T/emm combinations were represented by a single isolate during the entire study period. The remaining 8 were represented by more than one isolate each recovered in different years: T13 emm4, T13 emm77, and T12 emm28 were expressed by 3 isolates; T12 emm4, T(B3264) emm89, T1 emm4, T13 emm1, and T(nontypeable) emm1 were expressed by 2 isolates.