TABLE 2.
Summary of azole drug individual MICs and interaction interpretation using the ΣFIC
| Group | n | MIC (μg/ml)a
|
ΣFIC (interpretation)b
|
||||
|---|---|---|---|---|---|---|---|
| ITC | VRC | FLC | ITC-FLC | ITC-VRC | VRC-FLC | ||
| S | 8 | 0.438 | 0.531 | 800.0 | 0.818 (I) | 0.489 (S) | 0.781 (I) |
| G54 | 12 | 16.0 | 0.375 | 201.6 | 0.194 (S) | 0.189 (S) | 0.777 (I) |
| M220 | 8 | 16.0 | 1.375 | 1,280.0 | 2.000 (I) | 0.271 (S) | 1.956 (I) |
| A-KO | 2 | 0.060 | 0.350 | 113.4 | 0.910 (I) | 0.740 (I) | 0.758 (I) |
| B-KO | 1 | 0.250 | 0.500 | 640.0 | 1.000 (I) | 1.000 (I) | 0.500 (I) |
a
Geometric mean (three repetitions on three separate days).
b
Arithmetic mean (three repetitions on three separate days). S, synergistic; I, indifferent.