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. 2024 Jan 29;166(3):485–492. doi: 10.1007/s11060-024-04568-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Heatmap overview of next generation sequencing (NGS) gene panels in different centers. Seven centers provided detailed panel information. For the center with the broad 500 gene panel by default, only those genes present in at least one of the other panels are depicted. Essentiality is based on the fifth edition of the World Health Organization classification of tumors of the central nervous system (WHO CNS5) [2, 18]