TABLE 5.

Tac concentration/dose between baseline and period of azole co-therapy.

Triazole		Before/after co-therapy	During azole co-therapy	p
Voriconazole	Tac concentration (ng/μL)	5.31 ± 3.06	8.37 ± 4.39	<0.001
	Tac dose (mg/day)	2.86 ± 2.25	1.46 ± 1.19	<0.001
	Tac C/D (ng/μL/mg)	4.86 ± 6.35	10.62 ± 10.57	<0.001
Posaconazole	Tac concentration (ng/μL)	6.01 ± 2.79	7.63 ± 3.64	0.021
	Tac dose (mg/day)	3.21 ± 2.44	2.55 ± 2.17	0.356
	Tac C/D (ng/μL/mg)	3.36 ± 3.53	5.30 ± 4.42	0.027

C/D, dose-corrected through concentration; Tac, tacrolimus.