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Tumorigenicity of melanoma cell lines in mice injected with retroviruses expressing known H-RAS effector loop mutants
| H-RAS mutant | Doxa | No. of tumors/no. of mice |
|---|---|---|
| Vector | + | 4/4 |
| − | 0/4 | |
| H-RASV12S35 | − | 4/4 |
| H-RASV12G37 | − | 1/4 |
| H-RASV12C40 | − | 0/4 |
Melanoma cells were grown in vitro in the presence (+) or absence (−) of doxycycline (Dox).
