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. 2024 Feb 2;35(1):102131. doi: 10.1016/j.omtn.2024.102131

Table 1.

LNP-anti-miR103/107composition

Lipid composition of LNPs (molar ratio)
Formulation DSPC CHOL DODAP PEG2000-Cer16 DSPE-PEG-Mal Surface conjugation Anti-miR103/107theoretical loading (nmol/mg lipids)
LNP 1 1.8 0.8 0.4
LNP 1 1 1.8 0.8 0.4 27.6
LNP 2 1 1.8 2 0.4 41.4
LNP 3 1 1.8 0.8 0.2 0.2 Transferrin 27.6
LNP 4 1 1.8 2 0.2 0.2 Transferrin 41.4