Table 2.
Chromatographic conditions/method for Related Substances and Assay for selected samples by HPLC.
| S. No. | Drugs | Column | Related Substances |
Assay |
||||
|---|---|---|---|---|---|---|---|---|
| Flow rate (ml/min) | λmax (nm) | Injection Volume (µl) | Flow rate (ml/min) | λmax (nm) | Injection Volume (µl) | |||
| 1 | Irbesartan | 250X4.6 mm, C-18, 5µ | 1 | 220 | 15 | 1 | 220 | 15 |
| 2 | Losartan Potassium | 250X4 mm, C-8, 5µ | 1 | 237 | 20 | 1.5 | 235 | 10 |
| 3 | Olmesartan Medoxomil | 150X4.6 mm, C-18, 5µ (RS) | 1 | 215 | 10 | 1 | 215 | 20 |
| 250X4.6 mm, C-18, 5µ (Assay) | ||||||||
| 4 | Telmisartan | 150X4.6 mm, C-18, 5µ | 1 | 298 | 20 | 1.8 | 298 | 20 |
| 5 | Valsartan | 250X4.6 mm, C-18, 5µ | 1 | 273 | 10 | 1 | 273 | 10 |