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. 2024 Feb 20;24:234. doi: 10.1186/s12885-024-11985-5

Table 3.

IC50 value for 5-FU after treatment with the PPARG agonists pioglitazone, rosiglitazone and the PPARG inhibitor GW9662

Treatment IC50 (μM)
average + standard deviation
p-value
paired t-test
p-value
Wilcoxon-Rank test
HT29 Control 31.4 ± 8.2
Pio 80 μM 4.4 ± 0.8 < 0.0001 < 0.01
Rosi 80 μM 5.3 ± 0.7 < 0.0001 < 0.01
GW9662 10 μM 100.5 ± 69.9 0.03 < 0.01
SW403 Control 10.6 ± 1.9
Pio 80 μM 3.8 ± 0.6 < 0.0001 < 0.01
Rosi 80 μM 5.0 ± 1.7 < 0.001 < 0.01
GW9662 10 μM 18.8 ± 16.1 0.19 0.426