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. 2024 Feb 19;20(1):2315709. doi: 10.1080/21645515.2024.2315709

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© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 4. — 6-month stability of NDV-HXP-S with and without CpG 1018® adjuvant. NDV-HXP-S vaccine was prepared at 6 µg/mL S-antigen with and without 3 mg/mL CpG 1018® adjuvant in saline and held at 2°C to 8°C and 40°C. Samples were removed from temperature and tested for S-antigen content and stability by inhibition ELISA at selected timepoints. (a) NDV-HXP-S stability at 2°C to 8°C; (b) NDV-HXP-S stability at 40°C; (c) CpG 1018® adjuvant stability (integrity) at 2°C to 8°C and 40°C shown as a percentage of a CpG 1018® adjuvant standard tested at each time point; and (d) CpG 1018® adjuvant content at the beginning of the stability study. Methods provided by Dynavax technologies.