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Nasal wash IgA antibody responses. (A) Mouse vaccination regimen. (B) ELISA analysis of RBD-specific IgG antibody responses induced by vaccination in sera collected at Day 28 after vaccination (n = 4/group). (C) ELISA analysis of PR8-specific IgA antibody levels from nasal wash samples collected on Day 28 after vaccination (n = 4/group). (D) ELISA analysis of RBD-specific IgA antibody levels from nasal wash samples collected on Day 28 after vaccination (n = 4/group).
