. 2005 Apr 22;6:104. doi: 10.1186/1471-2105-6-104

Table 2.

Prediction results for 30 different GPCR subtypes with known coupling properties extracted from the gpDB database [18] that are not included in the training set [37]. The annotation of GPCR coupling properties in gpDB is based on data from the scientific literature. According to the gpDB classification scheme, G_gustand G_tG-proteins belong to the G_i/osubfamily and G_olfto the G_ssubfamily. The GPCR sequences were extracted from gpDB and parsed into our prediction server http://bioinformatics.biol.uoa.gr/PRED-COUPLE.

GPCR Subtype	Uniprot AC	observed	predicted
5-OXO-ETE receptor TG1019	Q8TDS5	G_i/o	G_q/11
Allatostatin receptor	Q9W4R0	G_i/o	G_i/oG_q/11
Apelin receptor	P35414	G_i/o	G_i/o
Gonadotropin releasing hormone I receptor	Q92644	G_q/11	G_i/o
Gonadotropin releasing hormone II receptor	Q8TCX8	G_q/11	G_q/11
Gustatory receptor 43	Q9JHE2	G_gust	G_i/o
Gustatory receptor GUST27	P34987	G_i/o	G_i/o
Neuromedin U1 receptor	Q9JIB2	G_q/11	G_q/11G_i/o
Neuromedin U2 receptor	Q9NRA6	G_q/11	G_q/11G_i/o
Nicotinic Acid receptor	Q8TDS4	G_i/o	G_i/o
Olfactory receptor 10A7	Q96R19	G_olf	G_s
Blue opsin	Q13877	G_t	G_i/o
Orexin 1 receptor	O43613	G_q/11	G_i/oG_q/11
Orexin 2 receptor	O43614	G_q/11	G_i/oG_q/11
Platelet activating factor receptor	P25105	G_i/oG_q/11	G_i/o
Prolactin-releasing peptide receptor	O75194	G_q/11	G_i/o
Trace amine receptor TAR	Q9P1P4	G_s	G_s
Trace amine receptor TAR-1	Q96RJ0	G_s	G_q/11G_sG_i/o
Trace amine receptor TAR-2	Q923Y7	G_s	G_sG_i/o
Trace amine receptor TAR-3	Q96RI9	G_s	G_i/oG_s
Urotensin II receptor	Q9UKP6	G_q/11	G_i/o
Gastric inhibitory peptide receptor	Q9UPI1	G_s	G_s
Glucagon Receptor	P47871	G_s	G_s
Glucagon like peptide receptor 2	O95838	G_s	G_s
Ghrelin receptor	Q96RJ7	G_q/11	G_q/11
Parathyroid hormone receptor 1	P49190	G_s	G_s
Parathyroid hormone receptor 2	Q03431	G_s	G_s
Secretin receptor	Q13213	G_s	G_s
Calcium-sensing receptor	P41180	G_i/oG_q/11	G_i/o
Taste receptor TASTE_TB334	Q62942	G_gust	G_i/o