Table 1. Baseline patient characteristics at the first questionnaire.
Characteristics (n = 586) | n (%) |
Female | 414 (70.6) |
Male | 172 (29.4) |
Age (mean years, SD) | 59.3 (12.1) |
Length (mean cm, SD) | 171.9 (9.4) |
Weight (mean kg, SD) | 76.5 (14.9) |
Concurrent autoimmune diseases | (n, %) |
Ankylosing spondylitis | 12 (2.0) |
Crohn’s Disease | 6 (1.0) |
Colitis ulcerosa | 3 (0.5) |
Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) | 1 (0.2) |
Sarcoidosis | 1 (0.2) |
Scleroderma | 4 (0.7) |
Sjögren | 1 (0.2) |
Systemic Lupus Erythematosus | 1 (0.2) |
Unknown | 1 (0.2) |
Comorbidities | (n, %) a |
Respiratory disorder | 77 (13.1) |
Cardiovascular disorder | 172 (29.4) |
Hypercholesterolemia | 123 (21.0) |
Psychiatric disorder | 31 (5.3) |
Cancer | 13 (2.2) |
Nervous system disorder | 19 (3.2) |
No comorbidity | 179 (30.6) |
Not specified | 53 (9.0) |
Smoking status | (n, %) |
Daily | 63 (10.8) |
Weekly | 9 (1.5) |
Monthly or less | 21 (3.6) |
Never | 490 (83.6) |
Not specified | 3 (0.5) |
RA-related comedication | (n, %) a |
Azathioprine | 18 (3.1) |
Hydroxychloroquine | 61 (10.4) |
Hydrocortisone | 3 (0.5) |
Leflunomide | 39 (6.6) |
Methotrexate | 291 (49.5) |
Prednisone | 78 (13.3) |
Sulfasalazine | 38 (6.5) |
No comedication | 123 (21.0) |
Not specified | 32 (5.5) |
Biological use | (n, %) |
Abatacept (T-cell costimulation inhibitor) | 31 (5.3) |
Adalimumab (TNF-alpha inhibitor) | 184 (31.4) |
Anakinra (IL-1 inhibitor) | 1 (0.2) |
Certolizumab pegol (TNF-alpha inhibitor) | 19 (3.2) |
Etanercept (TNF-alpha inhibitor) | 262 (44.7) |
Golimumab (TNF-alpha inhibitor) | 14 (2.4) |
Infliximab (TNF-alpha inhibitor) | 16 (2.7) |
Rituximab (anti-CD20) | 16 (2.7) |
Sarilumab (IL-6 inhibitor) | 1 (0.2) |
Secukinumab (IL-17A inhibitor) | 2 (0.3) |
Tocilizumab (IL-6 inhibitor) | 40 (6.8) |
IL = interleukin, RA = rheumatoid arthritis; SD = standard deviation, TNF = Tumor Necrosis Factor.
aAn individual patient could have no, one or multiple comorbidities and/or comedications.