Skip to main content
. 2024 Feb 20;19(2):e0296821. doi: 10.1371/journal.pone.0296821

Table 1. Baseline patient characteristics at the first questionnaire.

Characteristics (n = 586) n (%)
Female 414 (70.6)
Male 172 (29.4)
Age (mean years, SD) 59.3 (12.1)
Length (mean cm, SD) 171.9 (9.4)
Weight (mean kg, SD) 76.5 (14.9)
Concurrent autoimmune diseases (n, %)
Ankylosing spondylitis 12 (2.0)
Crohn’s Disease 6 (1.0)
Colitis ulcerosa 3 (0.5)
Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) 1 (0.2)
Sarcoidosis 1 (0.2)
Scleroderma 4 (0.7)
Sjögren 1 (0.2)
Systemic Lupus Erythematosus 1 (0.2)
Unknown 1 (0.2)
Comorbidities (n, %) a
Respiratory disorder 77 (13.1)
Cardiovascular disorder 172 (29.4)
Hypercholesterolemia 123 (21.0)
Psychiatric disorder 31 (5.3)
Cancer 13 (2.2)
Nervous system disorder 19 (3.2)
No comorbidity 179 (30.6)
Not specified 53 (9.0)
Smoking status (n, %)
Daily 63 (10.8)
Weekly 9 (1.5)
Monthly or less 21 (3.6)
Never 490 (83.6)
Not specified 3 (0.5)
RA-related comedication (n, %) a
Azathioprine 18 (3.1)
Hydroxychloroquine 61 (10.4)
Hydrocortisone 3 (0.5)
Leflunomide 39 (6.6)
Methotrexate 291 (49.5)
Prednisone 78 (13.3)
Sulfasalazine 38 (6.5)
No comedication 123 (21.0)
Not specified 32 (5.5)
Biological use (n, %)
Abatacept (T-cell costimulation inhibitor) 31 (5.3)
Adalimumab (TNF-alpha inhibitor) 184 (31.4)
Anakinra (IL-1 inhibitor) 1 (0.2)
Certolizumab pegol (TNF-alpha inhibitor) 19 (3.2)
Etanercept (TNF-alpha inhibitor) 262 (44.7)
Golimumab (TNF-alpha inhibitor) 14 (2.4)
Infliximab (TNF-alpha inhibitor) 16 (2.7)
Rituximab (anti-CD20) 16 (2.7)
Sarilumab (IL-6 inhibitor) 1 (0.2)
Secukinumab (IL-17A inhibitor) 2 (0.3)
Tocilizumab (IL-6 inhibitor) 40 (6.8)

IL = interleukin, RA = rheumatoid arthritis; SD = standard deviation, TNF = Tumor Necrosis Factor.

aAn individual patient could have no, one or multiple comorbidities and/or comedications.