Table 5. Gene Ontology terms related to biological process, cellular component and molecular function of the genes associated directly or indirectly with SNPs in the HFC from Nelore and Angus heifers.
| Category | GO ~ Term | Count | % | P Value | Genes | |
|---|---|---|---|---|---|---|
| Nelore | GOTERM_BP_FAT | GO:0006928 ~ cell motion | 5 | 11.4 | 0.02 | ROBO1, PRKDC, DCDC2, DNAH7, SLIT3 |
| GOTERM_BP_FAT | GO:0048870 ~ cell motility | 4 | 9.1 | 0.03 | ROBO1, PRKDC, DCDC2, DNAH7 | |
| GOTERM_BP_FAT | GO:0051674 ~ localization of cell | 4 | 9.1 | 0.03 | ROBO1, PRKDC, DCDC2, DNAH7 | |
| GOTERM_CC_FAT | GO:0044459 ~ plasma membrane part | 11 | 25.0 | 0.01 | EPHA5, ART3, CLCN3, ROBO1, KCNB2, SNTB1, SGCD, STIM1, ATP1A1, RIMS1, CTNNA3 | |
| GOTERM_CC_FAT | GO:0016010 ~ dystrophin-associated glycoprotein complex | 2 | 4.5 | 0.03 | SNTB1, SGCD | |
| Angus | GOTERM_BP_FAT | GO:0001822 ~ kidney development | 3 | 8.3 | 0.01 | PKHD1, FBN1, NID1 |
| GOTERM_BP_FAT | GO:0001655 ~ urogenital system development | 3 | 8.3 | 0.02 | PKHD1, FBN1, NID1 | |
| GOTERM_CC_FAT | GO:0043228 ~ non-membrane-bounded organelle | 12 | 33.3 | 0.00 | FNTB, TNS3, PARN, PKHD1, MYO16, RBM19, WDR1, MYH14, DNAH2, SHANK1, XRN2, CBS | |
| GOTERM_CC_FAT | GO:0043232 ~ intracellular non-membrane-bounded organelle | 12 | 33.3 | 0.00 | FNTB, TNS3, PARN, PKHD1, MYO16, RBM19, WDR1, MYH14, DNAH2, SHANK1, XRN2, CBS | |
| GOTERM_CC_FAT | GO:0005604 ~ basement membrane | 3 | 8.3 | 0.01 | FRAS1, FBN1, NID1 | |
| GOTERM_CC_FAT | GO:0044420 ~ extracellular matrix part | 3 | 8.3 | 0.02 | FRAS1, FBN1, NID1 | |
| GOTERM_CC_FAT | GO:0044430 ~ cytoskeletal part | 6 | 16.7 | 0.03 | FNTB, PKHD1, MYO16, MYH14, DNAH2, SHANK1 | |
| GOTERM_CC_FAT | GO:0005730 ~ nucleolus | 5 | 13.9 | 0.04 | TNS3, PARN, RBM19, XRN2, CBS | |
| GOTERM_CC_FAT | GO:0005856 ~ cytoskeleton | 7 | 19.4 | 0.04 | FNTB, PKHD1, MYO16, WDR1, MYH14, DNAH2, SHANK1 | |
| GOTERM_MF_FAT | GO:0004532 ~ exoribonuclease activity | 2 | 5.6 | 0.02 | PARN, XRN2 | |
| GOTERM_MF_FAT | GO:0016896 ~ exoribonuclease activity, producing 5'-phosphomonoesters |
2 | 5.6 | 0.02 | PARN, XRN2 | |
| GOTERM_MF_FAT | GO:0003779 ~ actin binding | 4 | 11.1 | 0.02 | MYO16, WDR1, MYH14, MYLK | |
| GOTERM_MF_FAT | GO:0005516 ~ calmodulin binding | 3 | 8.3 | 0.03 | ADCY1, MYH14, MYLK | |
| GOTERM_MF_FAT | GO:0003774 ~ motor activity | 3 | 8.3 | 0.03 | MYO16, MYH14, DNAH2 | |
| GOTERM_MF_FAT | GO:0016796 ~ exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 2 | 5.6 | 0.03 | PARN, XRN2 | |
| GOTERM_MF_FAT | GO:0046872 ~ metal ion binding | 14 | 38.9 | 0.04 | FRAS1, ADCY1, RBM20, FBN1, SYT9, PRKCH, NID1, FNTB, TNS3, PARN, EBF1, XRN2, MYLK, CBS | |
| GOTERM_MF_FAT | GO:0043169 ~ cation binding | 14 | 38.9 | 0.04 | FRAS1, ADCY1, RBM20, FBN1, SYT9, PRKCH, NID1, FNTB, TNS3, PARN, EBF1, XRN2, MYLK, CBS | |
| GOTERM_MF_FAT | GO:0043167 ~ ion binding | 14 | 38.9 | 0.04 | FRAS1, ADCY1, RBM20, FBN1, SYT9, PRKCH, NID1, FNTB, TNS3, PARN, EBF1, XRN2, MYLK, CBS |