Table 1.
Patient characteristics at diagnosis in the main analysis set
| Characteristic | N = 187 |
|---|---|
| Median age, years (range)a | 53.0 (22.0–81.0) |
| Ethnic group, n (%) | |
| Black | 1 (0.5) |
| Caucasian | 177 (94.7) |
| Other | 9 (4.8) |
| Median (IQR) BMI, kg/m2 | 26.0 (22.8–29.8) |
| Menopausal status (primary diagnosis), n (%) | |
| Premenopausal | 82 (43.9) |
| Perimenopausal | 14 (7.5) |
| Postmenopausal | 91 (48.7) |
| Employment status, n (%) | |
| Employed full-time | 56 (29.9) |
| Employed part-time | 47 (25.1) |
| Unemployed, not disease related | 12 (6.4) |
| Unemployed, disease related | 26 (13.9) |
| Retired | 39 (20.9) |
| Missing | 7 (3.7) |
| ECOG performance status, n (%) | |
| 0 | 133 (71.1) |
| 1 | 47 (25.1) |
| 2 | 3 (1.6) |
| Not evaluated | 4 (2.1) |
| Clinical T-stage at primary diagnosis, n (%) | |
| cT0/cTis (DCIS) | 1 (0.5)/2 (1.1) |
| cT1 | 23 (12.3) |
| cT1a/cT1b | 2 (1.1)/12 (6.4) |
| cT1c | 55 (29.4) |
| cT2 | 73 (39.0) |
| cT3 | 8 (4.3) |
| cT4/cT4d | 1 (0.5)/1 (0.5) |
| cTX | 9 (4.8) |
| Clinical N-stage at primary diagnosis, n (%) | |
| cN0/cN1mi | 116 (62.0)/3 (1.6) |
| cN1 | 48 (25.7) |
| cN2 | 4 (2.1) |
| cN2a/b | 1 (0.5)/1 (0.5) |
| cN3 | 1 (0.5) |
| cN3a | 1 (0.5) |
| cNX | 12 (6.4) |
| AJCC stage at primary diagnosis, n (%) | |
| TisN0M0 | 1 (0.5) |
| IA | 69 (36.9) |
| IIA | 55 (29.4) |
| IIB | 26 (13.9) |
| IIIA | 10 (5.3) |
| IIIB | 2 (1.1) |
| IIIC | 2 (1.1) |
| MX | 11 (5.9) |
| TX/NX | 11 (5.9) |
| WHO tumor grading at primary diagnosis, n (%) | |
| G1 | 3 (1.6) |
| G2 | 82 (43.9) |
| G3 | 92 (49.2) |
| GX | 10 (5.3) |
| Ki67 status,bn (%) | |
| High | 120 (64.2) |
| Low | 54 (28.9) |
| Unknown | 13 (7.0) |
AJCC, American Joint Committee on Cancer; BMI, body mass index; c, clinical; DCIS, ductal carcinoma in situ; ECOG, Eastern Cooperative Oncology Group; G, grading; IQR, interquartile range; mi, micro-metastasis; M, metastasis; N, lymph node; T, tumor; WHO, World Health Organization; X, status not determined.
aAt date of informed consent.
bAs per center standard definition.